主要参考文献
1.马丽媛,吴亚哲,王文,等.《中国心血管病报告2017》要点解读[J].中国心血管杂志,2018,23(1):3-6.
2.KORETZ RL. Assessing the evidence in evidence-based medicine[J]. Nutr Clin Pract,2019,34(1):60-72.
3.王家良,循证医学与临床医学[J].华西医学,2001(4):381-382.
4.中华医学会心血管病学分会心力衰竭学组,中国医师协会心力衰竭专业委员会与中华心血管病杂志编辑委员会.中国心力衰竭诊断和治疗指南2018[J].中华心血管病杂志,2018.46(10):760-789.
5.BELZ G G,BREITHAUPT-GRÖGLER K,OSOWSKI U. Treatment of congestive heart failure—current status of use of digitoxin[J]. Eur J Clin Invest,2001,31(2):10-17.
6.HELBER I,TUCCI P J. Digoxin:the results of the DIG study in the ⅩⅪ century[J]. Arq Bras Cardiol,2010,95(4):108-111.
7.RUIZ-HURTADO G,BANEGAS J R,SARAFIDIS P A,et al. Has the SPRINT trial introduced a new bloodpressure goal in hypertension?[J] Nat Rev Cardiol,2017,14(9):560-566.
8.KNIGHT D H. Efficacy of inotropic support of the failing heart[J]. Vet Clin North Am Small Anim Pract,1991,21(5):879-904.
9.TEERLINK J R,JALALUDDIN M,ANDERSON S,et al. Ambulatory ventricular arrhythmias in patients with heart failure do not specifically predict an increased risk of sudden death. PROMISE(Prospective Randomized Milrinone Survival Evaluation)Investigators[J]. Circulation,2000,101(1):40-46.
10.张潮,徐俊波.急性心力衰竭诊断治疗进展[J].心血管病学进展,2018. 39(6):994-998.
11.丁发明,王水强,华尉利,等.对《急性心力衰竭治疗药物临床试验技术指导原则》的解读[J].中国临床药理学杂志,2018.34(21):2580-2584.
12.王鸿懿.2018欧洲高血压防治指南解读[J].中国医学前沿杂志,2018,10(10):20-27.
13.国家基层高血压防治管理指南[J].中国循环杂志,2017,32(11):1041-1048.
14.SINGHSS,KANG PM. Mechanisms and inhibitors of apoptosis in cardiovascular diseases[J]. Curr Pharm Des,2011,17(18):1783-1793.
15.CHENG Y,TIAN H. Current Development Status of MEK Inhibitors[J]. Molecules,2017,22(10):E1551.
16.KENNEDY R A,KEMP T J,SUGDEN P H,et al. Using U0126 to dissect the role of the extracellular signalregulated kinase 1/2(ERK1/2)cascade in the regulation of gene expression by endothelin-1 in cardiac myocytes[J]. J Mol Cell Cardiol,2006,41(2):236-247.
17.李越凡,徐丹,李婷,等.p38MAPK信号通路的抑制减轻缺氧复氧环境下心肌细胞凋亡[J].中国循证心血管医学杂志,2018,10(7):861-869.
18.LI C,WANG T,ZHANG C,et al. Quercetin attenuates cardiomyocyte apoptosis via inhibition of JNK and p38 mitogen-activated protein kinase signaling pathways[J]. Gene,2016,577(2):275-280.
19.LIU W,DENG J,DING W,et al. Decreased KCNE2 Expression Participates in the Development of Cardiac Hypertrophy by Regulation of Calcineurin-NFAT(Nuclear Factor of Activated T Cells)and Mitogen-Activated Protein Kinase Pathways[J]. Circ Heart Fail,2017,10(6):e003960.
20.CORTESE J. Death watch Ⅱ:caspases and apoptosis[J]. Scientist,2001,15(5):24.
21.DEGTEREV A,BOYCE M,YUAN J. A decade of caspases[J]. Oncogene,2003,22(53):8543-8567.
22.VALLE R J,MAVRO A G,DEVARAKONDA T,et al. Reperfusion therapy with recombinant human relaxin-2(Serelaxin)attenuates myocardial infarct size and NLRP3 inflammasome following ischemia/reperfusion injury via eNOS-dependent mechanism[J]. Cardiovasc Res,2017,113(6):609-619.
23.ARIES A,WHITCOMB J,SHAO W,et al. Caspase-1 cleavage of transcription factor GATA4 and regulation of cardiac cell fate[J]. Cell Death Dis,2014,5:e1566.
24.KIM D Y,CHUNG S I,RO S W,et al. Combined effects of an antioxidant and caspase inhibitor on the reversal of hepatic fibrosis in rats[J]. Apoptosis,2013,18(12):1481-1491.
25.KATUNUMA N,OHASHI A,SANO E,et al. Catechin derivatives:specific inhibitor for caspases-3,7 and 2,and the prevention of apoptosis at the cell and animal levels[J]. FEBS Lett,2006,580(3):741-746.
26.HEIDARI F,VASUDEVAN R,MOHD ALI S E,et al. Association of insertion/deletion polymorphism of angiotensin-converting enzyme gene among Malay male hypertensive subjects in response to ACE inhibitors[J].J Renin Angiotensin Aldosterone Syst,2015,16(4):872-879.
27.OEMRAWSINGH R M,AKKERUIS K M,VAN VARK L C,et al. Individualized Angiotensin-Converting Enzyme(ACE)-Inhibitor Therapy in Stable Coronary Artery Disease Based on Clinical and Pharmacogenetic Determinants:The PERindopril GENEtic(PERGENE)Risk Model[J]. J Am Heart Assoc,2016,5(3):e002688.
28.NELVEG-KRISTENSEN K E,BUSK MADSEN M,TORP-PEOERSENC,et al. Pharmacogenetic Risk Stratification in Angiotensin-Converting Enzyme Inhibitor-Treated Patients with Congestive Heart Failure:A Retrospective Cohort Study[J]. PLoS One,2015,10(12):e0144195.
29.ALAZHARY N M,MORSY M M,AI-HARBI K M. Angiotensin-converting enzyme gene insertion deletion(ACE I/D)polymorphism in Saudi children with congenital heart disease[J]. Eur Rev Med Pharmacol Sci,2015,19(11):2026-2030.
30.YU H,ZHANG Y,LIU G. Relationship between polymorphism of the angiotensin-converting enzyme gene and the response to angiotensin-converting enzyme inhibition in hypertensive patients[J]. Hypertens Res,2003,26(11):881-886.
31.ŠLJIVIC J,PROTIC A,OTAŠEVIC B,et al. Multicriteria Optimization Methodology in Stability-Indicating Method Development of Cilazapril and Hydrochlorothiazide[ J]. J Chromatogr Sci,2017,55(6):625-637.
32.DENG G,GROBE J L. The renin-angiotensin system in the arcuate nucleus controls resting metabolic rate[J].Curr Opin Nephrol Hypertens,2019,28(2):120-127.
33.YAN L,ZHANG J D,WANG B,et al. Quercetin inhibits left ventricular hypertrophy in spontaneously hypertensive rats and inhibits angiotensin Ⅱ-induced H9C2 cells hypertrophy by enhancing PPAR-γ expression and suppressing AP-1 activity[J]. PLoS One,2013,8(9):e72548.
34.DESTERKE C,VOLDOIRE M,BONNET M L,et al. Experimental and integrative analyses identify an ETS1 network downstream of BCR-ABL in chronic myeloid leukemia(CML)[J]. Exp Hematol,2018,64:71-83.
35.CHEUNG SYA,RODGERS T,AARONS L,et al. Whole body physiologically based modelling of β-blockers in the rat:events in tissues and plasma following an i.v. bolus dose[J]. Br J Pharmacol,2018,175(1):67-83.
36.VIDAL F,DE SOUZA R C,FERREIRA D C,et al. Influence of 3 calcium channel blockers on gingival overgrowth in a population of severe refractory hypertensive patients[J]. J Periodontal Res,2018,53(5):721-726.
37.张瑞卿,杨文倩,余裕炳,等.硝苯地平骨架型缓释微丸在大鼠体内药代动力学及其与CYP3A4代谢酶活性的关系[J].中国药科大学学报,2018,49(4):427-432.