1.Waddington CH.The epigenotype.Endeavour，1942，1：18-20

2.Holliday R.Epigenetics，a historical Overview.Epigenetics，2006，1：76-80

3.Wolffe AP，Matzke MA.Epigenetics：regulation through repression.Science，1999，2869：481-486

4.Miyanari Y，Torres-Padilla ME.Epigenetic regulation of reprogramming factors towards pluripotency in mouse preimplantation development.Curr Opin Endocrinol Diabetes Obes，2010，17：500-506

5.Costa FF.Epigenomics in cancer management.Cancer Manag Res，2010，2：255-265

6.Dalgliesh GL，Furge K，Greenman C，et al.Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes.Nature，2010，463：360-363

7.Fernández-Morera JL，Calvanese V，Rodríguez-Rodero S，et al.Epigenetic regulation of the immune system in health and disease.Tissue Antigens，2010，76：431-439

8.Chen S，Sang N.Histone deacetylase inhibitors：the epigenetic therapeutics that repress hypoxia-inducible factors.J Biomed Biotechnol，2011，2011（1）：137-143

9.Rodríguez-Rodero S，Fernández-Morera JL，Fernandez AF，et al.Epigenetic regulation of aging.Discov Med，2010，10：225-233

10.Brunmeir R，Lagger S，Seiser C.Histone deacetylases HDAC1/HDAC2–controlled embryonic development and cell differentiation.Int J Dev Biol，2009，53：275-289

11.Hu Q，Friedrich AM，Johnson LV，et al.Memory in induced pluripotent stem cells：reprogrammed human retinal-pigmented epithelial cells show tendency for spontaneous redifferentiation.Stem Cells，2010，28：1981-1991

12.Bonasio R，Tu S，Reinberg D.Molecular signals of epigenetic states.Science，2010，330：612-616

13.Lam LL，Emberly E，Fraser HB，et al.Factors underlying variable DNA methylation in a human community cohort.Proc Natl Acad Sci U S A，2012，109（Suppl 2）：17253-17260

14.Portela A，Esteller M.Epigenetic modifications and human disease.Nat Biotechnol，2010，28：1057-1068

15.Lister R，PelizzolaM，DowenRH，et al.Human DNA methylomes at base resolution show widespread epigenomic differences.Nature，2009，462：315- 322

16.Zhou Q，Yang L，Wang Y，et al.TGF-beta a mediated transition of corneal fibroblasts from a proin flammatory state to a profibrotic state through modulation of histone acetylation.J Cell Physiol，2010，224（1）：135-143

17.Zhou P，Lu Y，Sun XH.Effects of a novel DNA methyltransferase inhibitor Zebularine on human lens epithelial cells.Mol Vis，2012，18：22-28

18.Zhou X，Ji F，An J，et al.Experimental murine myopia induces collagen type I alpha-1（COL1A1）DNA methylation and altered COL1A1 messenger RNA expression in sclera.Mol Vis，2012，18：1312-1324

19.Maloney SC，Antecka E，Granner T，et al.Expression of SIRT1 in choroidal neovascular membranes.Retina，2013，33：862-866

20.Yan D，Zhou X，Chen X，et al.Micro RNA-34a inhibits uveal melanoma cell proliferation and migration through downregulation of c-Met.Invest Ophthalmol Vis Sci，2009，50（4）：1559-1565

21.王晓琴，陈震，邢怡桥，等.MiR-145对视网膜母细胞瘤 Y79细胞增殖和凋亡的影响.中华眼视光学与视觉科学杂志，2012，14：153-156

22.Lee SK，Teng Y，Wong HK，et al.MicroRNA-145 regulates human corneal epithelial differentiation.PLoS One，2011，6（6）：e21249.

23.Hamon MA，Cossart P.Histone modifications and chromatin remodeling during bacterial infections.Cell Host Microbe，2008，4（2）：100-109

24.Xia M，Liu J，Wu X，et al.Histone methyltransferase Ash1l suppresses interleukin-6 production and inflammatory autoimmune diseases by inducing the ubiquitin-editing enzyme A20.Immunity，2013，39（3）：470-481

25.Li Y，Zhao M，Hou C，et al.Abnormal DNA methylation in CD4+ T cells from people with latent autoimmune diabetes in adults.Diabetes Res ClinPract，2011，94（2）：242-248

26.Rando TA，Chang H Y.Aging，rejuvenation，and epigenetic reprogramming：resetting the aging clock.Cell，2012，148（1-2）：46-57

27.Heyn H，Li N，Ferreira HJ，et al.Distinct DNA methylomes of newborns and centenarians.Proc Natl Acad Sci U S A，2012，109（26）：10522-10527

28.Coppieters N，Dragunow M.Epigenetics in Alzheimer’s disease：a focus on DNA modifications.Curr Pharm Des，2011，31（17）：3398-3412

29.Pieper HC，Evert BO，Kaut O，et al.Different methylation of the TNF-alpha promoter in cortex and substantia nigra：Implications for selective neuronal vulnerability.Neurobiol Dis，2008，32（3）：521-527

30.He S，Pirity MK，Wang WL，et al.Chromatin remodeling enzyme Brg1 is required for mouse lens fiber cell terminal differentiation and its denucleation.Epigenetics Chromatin，2010，3（1）：21

31.Zhou P，Lu Y，Sun XH.Zebularine suppresses TGF-beta-induced lens epithelial cell-myofibroblast transdifferentiation by inhibiting MeCP2.Mol Vis，2011，17：2717-2723

32.Yang X，Luo C，Cai J，et al.Neurodegenerative and inflammatory pathway components linked to TNF-α/TNFR1 signaling in the glaucomatous human retina.Invest Ophthalmol Vis Sci，2011，52（11）：8442-5452

33.Jünemann A，Lenz B，Reulbach U，et al.Genomic（epigenetic）DNA methylation in patients with open-angle glaucoma.Acta Ophthalmologica，2009，87：S244.

34.Sancho-Pelluz J，Alavi MV，Sahaboglu A，et al.Excessive HDAC activation is critical for neurodegeneration in the rd1 mouse.Cell Death Dis，2010，1：E24

35.Kaneko H，Dridi S，Tarallo V，et al.DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration.Nature，2011，7338（471）：325-330

36.Kulis M，Esteller M.DNA methylation and cancer.Adv Genet，2010，70：27-56

37.李阳，岳宏宇，刘文天，等.胃癌组织中微RNA-34b/c和微RNA-124a基因的甲基化.中华医学杂志，2011，91（23）：1640-1642.

38.Zhang J，Benavente CA，McEvoy J，et al.A novel retinoblastoma therapy from genomic and epigenetic analyses.Nature，2012，7381（481）：329-334

39.Cohen Y，Merhavi-Shoham E，Avraham RB，et al.Hypermethylation of CpG island loci of multiple tumor suppressor genes in retinoblastoma.Exp Eye Res，2008，86（2）：201-206

40.Dratviman-Storobinsky O，Cohen Y，Frenkel S，et al.The role of RASSF1A in uveal melanoma.Invest Ophthalmol Vis Sci，2012，53：2611-2619

41.Landreville S，Agapova OA，Matatall KA，et al.Histone deacetylase inhibitors induce growth arrest and differentiation in uveal melanoma.Clin Cancer Res，2011，18：408-416

42.Kim MS，Kwon HJ，Lee YM，et al.Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes.Nat Med，2011，7：437-443

43.Wang S，Li X，Parra M，et al.Control of endothelial cell proliferation and migration by VEGF signaling to histone deacetylase 7.Proc Natl Acad Sci U S A，2008，105：7738-7743

44.吕天娇，冯炜炜.血管生成相关因子在肿瘤中的表观遗传学变化.肿瘤，2012，32：301-307

45.SabatelC，Malvaux L，Bovy N，et al.MicroRNA-21 exhibits anti-angiogenic function by targeting RhoB expression in endothelial cells.PLoS One，2011，6 ：E16979.

46.Zhong Q，Kowluru RA.Role of histone acetylation in the development of diabetic retinopathy and the metabolic memory phenomenon.J Cell Biochem，2010，110（6）：1306-1313

47.Raffoux E，Cras A，Recher C，et al.Phase 2 clinical trials of 5-azacitidine，valproicacid，and all-trans retinoic acid in patients with high-risk acute myeloid leukemia or myelodysplastic syndrome.Oncotarget，2010，1：34-42

48.Wagner JM，Hackanson B，Lübbert M，et al.Histone deacetylase（HDAC）inhibitors in recent clinical trials for cancer therapy.Clin Epigenetics，2010，1：117-136

49.Berger SL，Kouzarides T，Shiekhattar R，et al.An operational definition of epigenetics.Genes Dev，2009，23：781-783

50.Dolinoy DC.The agouti mouse model：an epigenetic biosensor for nutritional and environmental alterations on the fetal epigenome.Nutr Rev，2008，66：S7-S11

51.Dolinoy DC，Weinhouse C，Jones TR，et al.Variable histone modifications at the A（ vy）metastable epiallele.Epigenetics，2010，7（5）：637-644

52.Shapiro JA.Mobile DNA and evolution in the 21st century.Mob DNA，2010，1（1）：4.

53.Belfort M，Marraffini L，Macfarlan T，et al.Mobile DNA：an evolving field.Mob DNA，2014，5：5-16

54.Shapiro JA.Constraint and opportunity in genome innovation.RNA Biol，2014，11：186-196.

55.Shapiro JA.Epigenetic control of mobile DNA as an interface between experience and genome change.Front Genet，2014，25（5）：87

56.Kazazian HH Jr，Moran JV.The impact of L1 retrotransposons on the human genome.Nature Genetics，1998，19（1）：19-24

57.Jacobson JW，Medhora MM，Hartl DL.Molecular structure of a somatically unstable transposable element in Drosophila.Proc Natl Acad Sci USA，1986，83：8684-8688

58.Mandal PK，Kazazian HH Jr，Shot S.Vertebrate transposons.Cell，2008，135，192-192

59.Kazazian HH Jr，Goodier JL.LINE drive：retrotransposition and genome instability.Cell，2002，110（3）：277-280

60.Kapitonov VV，Pavlicek A，Jurka J.Anthology of human repetitive DNA.Encyclopedia of Molecular Cell Biology and Molecular Medicine.Wiley-VCH Verlag GmbH & Co.KGaA Weinheim，2004，1：251-305.

61.Kazazian HH Jr，Wong C，Youssoufian H，et al.Haemophilia A resulting from de novo insertion of L1 sequences represents a novel mechanism for mutation in man.Nature，1988，6160（332）：164-166

62.Miki Y，Nishisho I，Horii A，et al.Disruption of the APC gene by a retrotransposal insertion of L1 sequence in colon cancer.Cancer Res，1992，52（3）：643-645

63.Feschotte C.Open Access Review of Mobile DNA-finding treasure in junk by Haig H Kazazian.Mobile DNA，2012，16（3）：1-2